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The ACS revised its guidance on PSA blood tests for prostate cancer screening

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The American Cancer Society updated its prostate cancer screening guideline Thursday, recommending a prostate-specific antigen (PSA) blood test every two years for average-risk men ages 50 to 69. It recommends annual testing from ages 45 to 69 for Black men and non-Black men with a strong family history of prostate cancer.

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CBS News said the update replaces guidance in place since 2010 that urged average-risk men to discuss whether and how often to test. The society cited advances in balancing early detection with potential harms, including MRI or validated biomarkers to guide biopsy decisions, and monitoring low-risk tumors.

Urology Times reported that men ages 45–69 with PSA levels of at least 3.0 ng/mL, and those ages 70–74 with levels of at least 6.5, should repeat testing within two weeks to three months. The ACS does not recommend screening at 75 or older, though very healthy men ages 75–79 may discuss continuing with a health-care provider.

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